We report the five known dopaminergic receptors, where they are located, the advantages and disadvantages of the employment in parkinsonian patients. The dopaminergic agonists were introduced to control the limitations of levodopa-increasing the therapheutic window. We analyse the pharmacocynetic efficacy and the side effects of cabergoline, ropinirole and pramipexole. Entretanto, devido a heterogeneidade das metodologias empregadas nos estudos, esses resultados devem ser analisados com reservas 6. Poewe W, Caraceni T. Dopamine agonists in the treatment of Parkinson's disease.

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Los inhibidores de la monoamino oxidasa B se emplean en el tratamiento de esta enfermedad en monoterapia o concomitantemente con levodopa. Los resultados evidenciaron propiedades interesantes del compuesto FCS Rev Neurol Paris. Projected number of people with Parkinson disease in the most populous nations, through Pharmacological treatment of Parkinson disease: A review. Prog Neurobiol. Emborg M. J Neurosci Methods. Gershanik OS. Improving L-dopa therapy: The development of enzyme inhibitors.

Mov Disord. Finberg J. Pharmacol Ther. Life Sci. Synthesis and evaluation of 6-methylphenylcoumarins as potent and selective MAO-B inhibitors. Bioorg Med Chem Lett. A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors. New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors.

Focusing on new monoamine oxidase inhibitors: Differently substituted coumarins as an interesting scaffold. Curr Top Med Chem. Eur J Med Chem. Neuroprotective effect of prenyloxycoumarins from edible vegetables. Neurosci Lett. Neurochem Int.

Philippens I. Drug Discov Today Dis Models. Chem Med Chem. ACS Chem Neurosci. Modified coumarins. Synthesis of substituted 5- 4-methoxyphenyl -7H-furo [3,2-g] chromenones. Chem Nat Compd. National Center for Biotechnology Information.

Accessed on: January 20, Different effects of 7-nitroindazole in reserpine-induced hypolocomotion in two strains of mice. Eur J Pharmacol. Ecstasy counteracts catalepsy in rats, an antiparkinsonian effect? Wei L, Chen L. Effects of 5-HT in globus pallidus on haloperidol-induced catalepsy in rats. Changes in ascorbic acid and malondialdehyde in rats after exposure to mercury. Bratis Lek Listy.

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Pharmacol Toxicol. Palabras clave: enfermedad de Parkinson, monoaminooxidasa, cumarinas, modelos animales, reserpina, levodopa, haloperidol, antioxidantes. Olaya, M. Redes sociales.


El análogo de cumarina 3-metil-7H-furo[3,2-g]cromen-7-ona, un posible agente antiparkinsoniano






ANTIPARKINSONIANOS - Biblioteca_1641526


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